Ariel Feldstein, M.D.
Professor and Division Chief, UCSD
Ariel Feldstein, M.D. is a renowned hepatologist and currently Professor of Pediatrics and Chief of the Division of Pediatric Gastroenterology, Hepatology, and Nutrition at the University of California San Diego (UCSD). Dr. Feldstein oversees one of the largest and most respected Divisions of Pediatric Gastroenterology in the Country with 23 current Faculty Members. Prior to joining UCSD in 2011, he was Director of Research for the Pediatric Institute at the Cleveland Clinic in Cleveland, Ohio. He has published over 140 peer-reviewed publications in leading scientific journals including seminal reviews on the disease biology of non-alcoholic steatohepatitis (NASH) and liver fibrosis.
Dr. Feldstein's research laboratory has provided key evidence to support the current accepted theory of the role of hepatic lipid compartmentation and lipotoxicity in the pathogenesis of steatohepatitis development. Recently, he characterized a pathogenic role of NLR inflammasomes in liver inflammation and fibrosis. His lab has established cell-free systems, cell culture systems, precision-cut liver slices and murine models of steatohepatitis to test novel therapies. He has also pioneered the development of non-invasive blood tests to monitor liver damage. Dr. Feldstein has contributed to the development of preclinical, translational and clinical research protocols for a number of non-invasive tests and therapeutic agents.
Dr. Feldstein has been the recipient of many awards, including the AGA Research Scholar Award, the Research Excellence in GI and Liver (REGAL) Award, The Cleveland Clinic Innovator Award, and Best Doctors in America. He is a member of the American Society for Clinical Investigation (ASCI) and the Society for Pediatric Research (SPR). He is currently Associate Editor of Hepatology Communications and Seminars in Liver Disease and previously served in an editorial capacity for Hepatology and Journal of Hepatology. He has held various leadership roles in the American Gastroenterological Association (AGA) and the American Association for the Study of Liver Diseases (AASLD) including serving as member of the Publications Committee (AASLD), ALF/AASLD Research Awards Committee, and the Hepatology Editor Selection Committee.