Scientific Advisory Board
Dr. Scott L. Friedman
Dr. Scott L. Friedman is the Dean for Therapeutic Discovery and Chief of the Division of Liver Diseases, at the Icahn School of Medicine at Mount Sinai. He has performed pioneering research into the underlying causes of scarring, or fibrosis associated with chronic liver disease, affecting millions worldwide. Dr. Friedman was among the first to isolate and characterize the hepatic stellate cell, the key cell type responsible for scar production in liver. His work has spawned an entire field that is now realizing its translational and therapeutic potential, with new anti-fibrotic therapies for liver disease reaching clinical trials. Dr. Friedman’s work has been continuously funded by the NIH since 1985.
A 1979 graduate of the Icahn School of Medicine at Mount Sinai, he served as the President of Alpha Omega Alpha Honor Society, then was a Medical Resident at the Beth Israel Hospital, Harvard Medical School, Boston, followed by a Gastroenterology Fellowship at UCSF before assuming a faculty position there which he held for ten years. During a 1995-96 sabbatical from UCSF he was a Senior Fulbright Scholar and Visiting Professor at the Weizmann Institute of Science in Israel, in the laboratory of Professor Moshe Oren. Dr. Friedman has given invited honorary lectures throughout the world and has been a named lecturer or Visiting Professor at over 30 institutions worldwide. He is widely recognized as a dynamic, effective speaker, and is also a respected author, with over 300 peer-reviewed publications. Dr. Friedman was a recipient in 1993 of the Saul Horowitz, Jr. Outstanding Alumnus Award from Mount Sinai. In 2003, Dr. Friedman was honored with the International Hans Popper Award by the Falk Foundation in Freiburg, Germany, in recognition of his outstanding contributions to the understanding of liver disease and its treatment. He has mentored over 75 postdoctoral fellows and students, most of who remain in academic training programs or faculty. In 2012 he was awarded the European Association for the Study of Liver Diseases International Recognition Award in Barcelona, Spain, and in 2013 he was awarded the Shanghai Magnolia Gold Award by the Mayor of Shanghai and the China Friendship Award from the Premier of China in 2014 in recognition of his efforts to improve the health of the residents of Shanghai and China through his research achievements. He received the Distinguished Achievement Award from the AASLD in 2016.
Dr. Friedman has been a member of the American Society of Clinical Investigation since 1995, the Association of American Physicians since 2004, and was elected as a Fellow of the American Gastroenterological Association in 2008, the Am. College of Physicians in 2013, the American Assn. for the Study of Liver Diseases in 2014 and the American Association for the Advancement for Science in 2015.
Gregory J. Gores, M.D.
Gregory J. Gores, M.D., is Executive Dean for Research at Mayo. He also serves as Chair of the Division of Gastroenterology and Hepatology and holds the academic rank of professor of physiology and medicine. He is recognized with the distinction of a named professorship, the Reuben R. Eisenberg Professorship.
Dr. Gores is a quintessential, senior academician; a "quadruple threat" with contributions to research, clinical practice, education, and leadership. His research contributions include sustained federal funding (greater than 25 years), over 600 publications, an H-index of 110, and over 35,000 citations. Based on these accomplishments, he was appointed as a Distinguished Mayo Investigator. His clinical focus on hepatobiliary neoplasia has led to pioneering work employing novel protocols for cholangiocarcinoma combined with liver transplantation. Educational activities include mentoring over 75 fellows, and directing a liver transplant fellowship program. These activities have been recognized by receipt of an American Gastroenterological Association Mentorship Award. Extramural leadership positions include past presidency of the American Association for the Study of Liver Disease (AASLD) and the International Liver Cancer Association; he is a current member of the American Gastroenterological Association Governing Board. Intramural positions include serving as past Chair of the Gastroenterology and Hepatology Division at Mayo Clinic Rochester, Medical Director of the Liver Transplant Program, and current Executive Dean for Research across the Mayo enterprise. His stature and accomplishments were recently recognized by the Mayo Alumni Association and the AASLD where he received the Plummer Award for excellence and the distinguished service award, respectively.
Dr. Nizar N. Zein
Dr. Nizar N. Zein is the Chief of Hepatology and Chairman and Medical Director of Global Patient Services at the Cleveland Clinic. He is also the inaugural holder of the Mikati Foundation Endowed Chair in Liver Disease and Transplantation. Dr. Zein’s research focuses on improving disease and treatment outcome in patients with the Hepatitis C virus and fatty liver disease before and after liver transplantation. He has authored over 200 publications, and has been the Principal Investigator of several large clinical trials. He holds several patents and established a research group at Cleveland Clinic focused on 3D printing of solid organs. His research has been supported multiple funding sources including the Mikati Family Endowment in Liver Diseases at the Cleveland Clinic.
Dr. Zein received his medical degree in 1986 at the University of Tishreen School of Medicine in Syria. Prior to joining Cleveland Clinic, he completed postgraduate training with internships, residencies and fellowships at Case Western Reserve University, the Medical College of Ohio and the Mayo Clinic Foundation. He served as a Staff Physician and Clinical Investigator at the Mayo Clinic until he joined the Cleveland Clinic in 2002.
Dr. Zein is the recipient of numerous honors and has served in several leadership committees at Cleveland Clinic, including his recent appointment to the Board of Governors. His honors include the American Liver Foundation Scholar Award and the Cleveland Clinic Innovator Award. He has been recognized for academic excellence by the Syrian American Medical Society and honored for his leadership and community service by the Ana G. Mendez University of Puerto Rico as the recipient of Presidential Medal in 2011. He was elected to the Board of Governors of the Cleveland Clinic in 2015.
Dr. Zein has served as the Editor of “The Year in Gastroenterology and Hepatology” associate editor of the American Journal of Gastroenterology, Special Section Editor of "Liver Transplantation" and an editorial board member of Hepatology and Gastroenterology & Hepatology.
An avid educator, Dr. Zein is Training Director for Sawiris Family Endowment for International Training in Liver Diseases. He has been recognized for his commitment to educating fellows and residents at Cleveland Clinic with the Distinguished Faculty Award for Research Mentorship and was awarded the Cleveland Clinic Lerner College of Medicine Teacher of the Year in 2008.